A neurologist grapples with aducanumab

We Search It For You January 26, 2022 No Comments

A neurologist grapples with aducanumab

I have been following the controversy surrounding the approval of the new Alzheimer’s drug aducanumab with great interest.  Until a year and a half ago, I worked as a neurologist in an adult general neurology clinic.   Many of my patients had dementia.  While I thoroughly enjoyed seeing these patients and their family members, I often felt helpless when treating them.  When I left clinical practice to explore a non-clinical career in the pharmaceutical industry, I envisioned helping patients with neurological conditions by bringing much-needed drugs to market.  Drugs like aducanumab. Aducanumab is the first disease-modifying drug approved for Alzheimer’s disease (AD) and the first AD medication to be approved in nearly two decades.  This should be exciting.  Instead, I find aducanumab’s approval both confusing and worrisome.  Simply stated, the drug has significant side effects, and it is unclear whether it has meaningful clinical benefit.  Despite the eleven-person neurological advisory board […]

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Improve Your Food Service Bottom Line with These 7 Financing Solutions

We Search It For You January 26, 2022 No Comments

Improve Your Food Service Bottom Line with These 7 Financing Solutions

Written by Justine NightingaleWednesday, January 26, 2022 at 05:00am CST Pay attention to all of your costs when looking at food service financing solutions. What is your bottom line? The dictionary says the bottom line is the final result or outcome. This is ultimately the sustainability of your restaurant. This also refers to the last line on your restaurant’s balance sheet – where you show profit and loss and your net operating income. For your food service business, the bottom line represents success, and it represents the continuation of your business. (tweet this) In this article we look at how to improve your food service bottom line with these seven financing solutions. #1: Change Your Pricing The first and easiest food service financing solution is to adjust your menu pricing. Before you do this, take a look at a few things: Research the competition. Look for similar restaurants. Consider your […]

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Ford begins E-Transit production, touts electric commercial vehicle strategy

We Search It For You January 26, 2022 No Comments

Ford begins E-Transit production, touts electric commercial vehicle strategy

Ford Motor Co Chief Executive Jim Farley won applause from Wall Street by increasing the production target for the automaker’s electric F-150 to 150,000 a year, more than three times the original number. Now, Farley wants investors and commercial vehicle customers to pay more attention to the software and services Ford wants to sell with those trucks, as well as to the company’s electric Transit vans and its portfolio of combustion engine commercial vehicles. Ford has started production of the E-Transit cargo van at its factory in Kansas City, Missouri, with first deliveries expected within weeks, and it stands ready to fill an existing 10,000 orders. Which is only the beginning — Ford has previously estimated that the market for electric commercial vans will be 1.1 million sales by the end of 2030. And Ford will have a big chunk of that market: It currently has 40% market share in […]

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Watch them in a drag race

We Search It For You January 26, 2022 No Comments

Watch them in a drag race

Now that the Lucid Air is a practical reality, there’s a looming question: how well does it fare in a drag race against the other well-known electric luxury sedan, Tesla’s Model S Plaid? You now have a better idea. DragTimes has shared a long-teased video of a quarter-mile faceoff between the Air and Model S Plaid, and the outcome is at once expected but still full of insights. It won’t shock you to hear the Model S Plaid wins three of the four runs, including one with a rolling start. It has a shorter claimed 0-to-60 time (1.99 seconds versus 2.5), and its lighter curb weight (4,828 pounds versus about 5,200), helps offset the horsepower deficiency. The Tesla didn’t have its drag strip prep mode enabled, either. If you’re fortunate enough to cross-shop these EVs, the Model S is still your pick for raw acceleration. The Lucid Air still holds […]

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the quest for positive reviews [PODCAST]

We Search It For You January 26, 2022 No Comments

the quest for positive reviews [PODCAST]

“Studies show that those physicians with negative online reviews were more often scored poorly due to non-physician specific causes. In my career, I’ve read comments from patients that said they were not satisfied with their provider because they didn’t like the color of the walls in the exam room. Another mentioned that tea wasn’t offered in the waiting room, just coffee. Surveys are not necessarily bad, but they have changed the way we interact with patients. Doctors are now feeling pressured to provide care patients don’t need because of fears of bad patient satisfaction scores or negative reviews online. This causes more stress on health care professionals. In a national study, 78 percent of clinicians said patient satisfaction scores moderately or severely affected their job satisfaction negatively, and 28 percent said the scores made them consider quitting.” Peter Valenzuela is a family physician and author of Doc-Related: A Physician’s Guide to Fixing […]

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2023 Toyota Sequioa reveals total redesign, hybrid turbo V6, Capstone trim

We Search It For You January 26, 2022 No Comments

2023 Toyota Sequioa reveals total redesign, hybrid turbo V6, Capstone trim

The all-new 2023 Toyota Sequoia has a lot of work to do if it has any chance of catching up with the sales leaders in the full-size SUV segment. As is the case with the 2022 Toyota Tundra upon which it’s based, the Japanese automaker’s biggest vehicles just don’t come close to the sales figures of their American competitors.  With 8,070 units sold, the Sequoia sat beneath the Nissan Armada at the very bottom of the sales chart in 2021. To put things into perspective, last year Chevy sold over 106,000 Tahoe SUVs, plus another 48,000 Suburbans. The GMC Yukon is nearly the same thing, and that adds another 82,000 units to the tally. The Ford Expedition and Lincoln Navigator handily outsell the Sequioa. And the Jeep Wagoneer, which just went on sale at the tail end of 2021, more than doubled Sequoia sales in the month of December.  Those […]

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North American VW Passat truly dead as production ends

We Search It For You January 25, 2022 No Comments

North American VW Passat truly dead as production ends

Volkswagen announced the end of North American Passat production last July, and the final models rolled off the Chattanooga assembly line back in December. In total, the Chattanooga factory built more than 800,000 examples of the Passat since the start of production in 2011. The Passat and the Chattanooga plant are closely associated, as not only was it the start of U.S. Passat production, but it was the start of the U.S. getting a completely unique Passat model. It was notably larger than its European namesake, and it was made more affordable. While it didn’t totally please car critics, it resonated with buyers at least for a while. In 2011, the final year of European-style Passat sales in the U.S., the company only sold 22,835. The following year, with the introduction of the American Passat, 125,212 examples found homes. That was the best-selling year for the American Passat, though, as […]

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5 science-backed strategies an allergist-mom is using to protect her family’s health

We Search It For You January 25, 2022 No Comments

5 science-backed strategies an allergist-mom is using to protect her family’s health

Like most parents, my children are my world. I would do anything to protect them and keep them healthy. It is Darwinian. Instinctual. Most of us get by with a combination of sage advice from generations past interspersed with a “know better do better” approach. Personally and professionally, I encountered this duality pretty quickly. In March 2016, my husband and I hopped on a plane to Los Angeles with our 4-month-old daughter with the purpose of both visiting grandparents and attending the American Academy of Allergy, Asthma and Immunology meeting. A few months prior, the LEAP (Learning Early About Peanut Allergy) trial was published. The old paradigm of avoiding potentially allergenic foods was tossed aside as new data emerged. As this data was extensively discussed, debated, and expanded upon during that meeting, you better bet that as soon as Charlotte could sit up, she was the poster child for early […]

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What’s New in Appraisal Membership: January 2022

We Search It For You January 25, 2022 No Comments

What’s New in Appraisal Membership: January 2022

McKissock’s Unlimited Learning Members enjoy 24/7 access to a wide variety of online appraisal classes, webinars, videos, podcasts, checklists, job aids, and other resources. Plus, we’re adding to our library each month so that you get the most current and relevant information to grow your real estate appraisal career. Do you already have an Unlimited Learning Membership? Here are five new appraisal webinars and videos available right now under the “Learning Library” tab in your McKissock Dashboard. Not yet a member? Learn about the benefits of membership. Recorded webinars Turn Your Appraisal Efforts into Cash – An Inside Look at Anow In this webinar recording, Anow’s President Marty Haldane discusses what pieces of data will help you better understand your business, what tools and tech you need to make sure you’re turning your appraisal efforts into cash, and what parts of the appraisal process Anow software covers. Fannie Mae Q4 […]

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Cadillac Lyriq first pre-production car rolls off the line

We Search It For You January 25, 2022 No Comments

Cadillac Lyriq first pre-production car rolls off the line

GM President Mark Reuss hopped on LinkedIn to celebrate the first pre-production Cadillac Lyriq electric crossover coming off the line at the Spring Hill Manufacturing plant. The facility, wholly devoted to the Saturn brand from beginning operations in 1990 to 2007, has built the Cadillac XT5, XT6, and GMC Acadia crossovers of late. A little more than a year ago, GM invested $2 billion to convert the Tennessee plant to battery-electric vehicle assembly. The Cadillac Lyriq is not only the first of a number of Ultium-based products to come from there, but Reuss said the CUV is nine months ahead of schedule and entering the portal for customer deliveries “in a few months.” The Lyriq Debut Edition is the third GM product utilizing the new Ultium platform, after the Bright Drop electric delivery van and electric GMC Hummer. The limited-edition Lyriq launch model sold out in just over 10 minutes […]

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